The Russian annexation of Crimea may be in direct contravention of international agreements but is popular in Russia and almost certain to hold. Given tensions within Ukrainian society and its weak transitional government, there remains some risk of further intervention in eastern Ukraine and possibly the Trans-Dniester break-away region of Moldova. Even if there is no further escalation in the crisis, the deterioration in EU/Russian and US/Russian relations is of great concern, not least in relation to two aspects of Middle East security – the Syrian civil war and the Iran nuclear negotiations.